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Chester County Health Department The Chester County Health Department and Department of Drug and Alcohol Services is sharing the US Drug Enforcement Administration’s (DEA) recent Public Safety Alert regarding the Widespread Threat of Fentanyl Mixed with Xylazine. The U.S. DEA warns of a sharp increase in the trafficking of fentanyl mixed with xylazine. Xylazine, also known as “Tranq”, is FDA-approved for use in animals as a sedative and pain reliever. Xylazine is not safe for use in humans and may result in serious and life-threatening side effects. DEA’s Laboratory System reports that in 2022 approximately 23% of fentanyl powder and 7% of fentanyl pills seized by the DEA contained xylazine. Xylazine and fentanyl drug mixtures place users at a higher risk of suffering a fatal drug poisoning. The side effects of xylazine appear to be similar to those commonly associated with opioid use, making it difficult to distinguish opioid overdoses from xylazine exposure, and routine toxicology screens do not detect xylazine. Because xylazine is not an opioid, naloxone (Narcan) does not reverse its effects. Healthcare professionals and first responders should be cautious of possible xylazine inclusion in fentanyl, heroin, and other illicit drug overdoses, as naloxone may not be able to reverse its effects. Healthcare professionals and first responders must be vigilant to avoid accidental contact with fentanyl from overdose victims which may cause overdose and death to those that come into contact. It is not known at this time whether the xylazine being used is illicitly produced (unapproved) or diverted from the animal drug supply. FDA encourages health care professionals and patients to report adverse events in humans associated with possible illicit xylazine exposure to FDA’s MedWatch Adverse Event Reporting program (www.fda.gov/medwatch/report.htm) Access the complete information at: DEA Public Safety Alert FDA alerts health care professionals of risks to patients exposed to xylazine in illicit drugs FDA letter to stakeholders providing clinical information about the risks of severe, necrotic skin ulcerations from repeated xylazine exposure, possible withdrawal symptoms, and xylazine’s interference with successful treatment of opioid overdoses. Many organizations collaborate throughout Chester County to prevent overdoses and support recovery. Access local resources at: Chester County Department of Drug and Alcohol Services Chester County Overdose Prevention Taskforce Access to free Narcan If you have questions about this guidance, please contact the Chester County Health Department – 610-344-6452 or Department of Drug and Alcohol Services at 610-344-6620. Please help circulate this information by sharing with your colleagues and partners.

Dear Chester County Medical Society Members, Looking for a little downtime? Too long since you socialized with your physician colleagues? Ready for that much-needed break with friends? Join us at the CCMS monthly SCRUM social held on the Last Thursday of each month. This month enjoy food, drinks, and camaraderie Thursday evening April 27th, 5-9 PM at Dr. Bruce Colley's Orchard, 1175 Valley Creek Road, Downingtown, PA. Click here for directions. RSVPs are not required. Questions? Please email Lynne Stilley at Lastilley@gmail.com Come out and join the fun! Lynne Stilley Executive Director Chester County Medical Society

The 27th Annual Pennsylvania Immunization Conference (PIC 2023) registration’s open: 27th Pennsylvania Immunization Conference - Penn State College of Medicine Continuing Education (psu.edu) for your consideration in attending and sharing with staff, colleagues, providers, vendors, stakeholders, and promoting via networks and partnerships. DATE: Thursday, June 15, 2023. TIME: 8:30 a.m. – 4:30 p.m. 7:30 a.m.: Check in, Refreshments, Exhibits, and Network. LOCATION: Hershey Lodge, Hershey, PA. Agenda topics with national, state, and local speakers, continuing education credits (CECs), costs, deadlines, and local hotels are included in the registration link. Attendance Options: In-person and virtual/live. REGISTRATION: Visit: 27th Pennsylvania Immunization Conference - Penn State College of Medicine Continuing Education (psu.edu). PIC 2023 Conference Exhibitor: Contact: REQUEST INFORMATION regarding course #J6900 if you are interested in being a PIC 2023 Conference Exhibitor. QUESTIONS: Contact: ContinuingEd@PennStateHealth.psu.edu. Thank you. My Best, Candance Sanderson, M.Ed. Candance Sanderson, M.Ed. | Public Health Program Administrator Division of Immunizations l Vaccines for Children (VFC) Program Pennsylvania Department of Health | Bureau of Communicable Diseases 625 Forster Street, Rm 1026 Harrisburg, PA 17120-0701 Email: cansanders@pa.gov VFC webpage

Join us for the Monthy SCRUM Social Night In the News Widespread Threat of Fentanyl Mixed with Xylazine - Chester County Health Department Chester County Health Department The Chester County Health Department and Department of Drug and Alcohol Services is sharing the US Drug... Join CCMS Tonight~ Thursday April 27th 5-9 PM at Dr. Bruce Colley's Orchard for the Scrum Social Dear Chester County Medical Society Members, Looking for a little downtime? Too long since you socialized with your physician colleagues?... The 27th Annual Pennsylvania Immunization Conference (PIC 2023) Registration is Open The 27th Annual Pennsylvania Immunization Conference (PIC 2023) registration’s open: 27th Pennsylvania Immunization Conference - Penn... Who We Are Supporting Physicians and Their Patients in Chester County, Pennsylvania since 1828. ​ ​ Click here Winter Edition Chester County Medicine Click here Click here Contact Lynne Stilley Executive Director EMAIL ADDRESS chestercomedsoc@gmail.com TELEPHONE NUMBER ​​610-495-9190 PHYSICAL ADDRESS Chester County Medical Society 1050 Airport Road PO Box 5344 West Chester PA 19380-5344 Pennsylvania, United States